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Afflicted Suffering from a serious illness or injury ■ "The athlete was afflicted with a sprained ankle and had to withdraw from the competition."; Experiencing misfortune, hardship, or suffering ■ "After losing their job, the family was afflicted with financial difficulties and had to move to a smaller house."; Cursed or ill-fated ■ "The team's losing streak seemed like an affliction that they couldn't shake off."